Endotoxin -- a component of bacteria believed to trigger an immune response in humans -- is found in dust.
University of Cincinnati College of Medicine researchers found persistent wheezing (an early warning sign of asthma and other lung conditions) in 36 percent of 3-year-olds who were exposed to high levels of traffic pollution and indoor endotoxin as infants.
In comparison, wheezing was seen in 11 percent of children exposed to low levels of outdoor and indoor allergens as infants, and in 18 percent of children exposed to high levels of traffic pollution and low levels of indoor endotoxin. Endotoxin exposure alone appeared to have little effect on children, the study authors noted.
"There is a clear synergistic effect from co-exposure to traffic-related particles and endotoxin above and beyond what you would see with a single exposure that can be connected to persistent wheezing by age 3," study author Patrick Ryan, a research assistant professor of environmental health, said in a university news release. "These two exposure sources -- when simultaneously present at high levels -- appear to work together to negatively impact the health of young children with developing lungs."
"Traffic-related particles and endotoxin both seem to trigger an inflammatory response in the children monitored in this study. When put together, that effect is amplified to have a greater impact on the body's response," Ryan explained. "The earlier in life this type of exposure occurs, the more impact it may have long term. Lung development occurs in children up through age 18 or 20. Exposure earlier in life to both endotoxin and traffic will have a greater impact on developing lungs compared to adults whose lungs are already developed."
The findings are published in the Dec. 1 issue of the American Journal of Respiratory and Critical Care Medicine.
More information
The American Academy of Allergy, Asthma and Immunology offers tips for the prevention of allergies and asthma in children.
-- Robert Preidt
SOURCE: University of Cincinnati Academic Health Center.
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Steve Zivolich, M.A., the owner/operator of Guaranteed Property Inspection and Mold Investigation Inc. has been providing property and environmental inspections for over 13 years in Orange County and Southern California.
Steve Z. has performed over 6,000 home inspections, mold, energy and environmental inspections and is fully certified and insured to meet all your inspection needs. He personally provides all field inspection services and as a result is able to maintain the highest Better Business Bureau rating of A+.
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Please take the time to read through Steve's home inspector credentials and qualifications as this is so important when hiring an inspector. Don't focus on price alone, focus on value, quality, experience and professionalism. When you hire an inspector, any inspector, you are hiring their individual knowledge, experience and qualifications so make sure you hire the best, not just the cheapest. We are confident that you will be Steve's next satisfied customer.
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Please take the time to read through Steve's home inspector credentials and qualifications as this is so important when hiring an inspector. Don't focus on price alone, focus on value, quality, experience and professionalism. When you hire an inspector, any inspector, you are hiring their individual knowledge, experience and qualifications so make sure you hire the best, not just the cheapest. We are confident that you will be Steve's next satisfied customer.
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